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Civicor 120mg
(out of stock) |
Verapamil hcl |
Douglas NEW ZEALAND |
200 tabs |
US$52 |
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Out Of Stock |
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Civicor Isoptin 40mg |
Verapamil hcl |
Douglas NEW ZEALAND |
150 tabs |
US$44 |
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Isoptin 40mg |
Verapamil hcl |
Knoll Pharmaceuticals (Switzerland) |
50 tabs |
US$33 |
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Isoptin 80mg |
Verapamil hcl |
Knoll Pharmaceuticals (Switzerland) |
50 tabs |
US$64 |
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Isoptin SR SR 240mg |
Verapamil hcl |
Knoll Pharmaceuticals (Switzerland) |
30 tabs |
US$66 |
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Verapine 40mg |
Verapamil hcl |
Berlin Pharma |
200 tabs |
US$44 |
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Verapine 80mg |
Verapamil hcl |
Berlin Pharma |
110 tabs |
US$44 |
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Verapine SR 240mg |
Verapamil hcl |
Berlin Pharma |
60 caps (6x10) |
US$56 |
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Out Of Stock |
Classification
Anti-Anginal Drugs / Calcium Antagonists / Other Antihypertensives
Indications
Lited in Dosage.
Dosage
Adult Essential hypertension Isoptin tab one 80-mg tab tid.Max: 480 mg/day in divided doses. Isoptin SR tab 1 tab inthe morning. If required, after 1 wk increase up to 2 tab/day in divided doses.Chronic stable & unstable angina, angina at rest including vasospastic angina; angina pectoris after MI; prophylaxis of supraventricular tachyarrhythmias Isoptin tab 80 mg tid-qid; in oral long-term treatment, max: 480 mg daily. Hypertensive crises, treatment of supraventricular tachyarrhythmias, acute coronary insufficiency (coronary spasm) Isoptin amp 5 mg slow IV to be repeated after 5-10 min, if required. Drip infusion to maintain the theapeutic efect: 5-10 mg/hr on ave up to a total dose of 100 mg/day.
Contraindications
CV shock, complicated acuteMI, severe conduction disorders (2nd & 3 rd degree AV block, AV block), sick sinus syndrome, heart failure, atrial fibrillation/flutter & simultaneous preexcitation syndrome. Myasthenia gravis.
Precautions
1st degree AV block, bradycardia, hypotension. May impair ability to drive or operate machinery. Pregnancy, lactation. Severe impairment of liver function. Show down markedly the elimination of alcohol & prolongs the duration of alcohol.
Adverse Reactions
Constipation, dizziness, nausea. Rarely, vertigo, headache, hypotension, ankle edema, flushing, fatigue, nervousness, erythromelalgia, paraesthesia, neuropathy; bradycardiac arrhythmias, CHF, dyspnea, raised prolactin levels, single cases of galactorrhea. Very rarely, myalgia, arthralgia; allergic skin reations; purpura, photosensitisation dermatitis, gynecomastia, reversible increase in transaminases &/or alkaline phosphatase, relevant impairment of glucose tolerance; gingival hyperplasia. Tachycardia, palpitations, impotence. Tinnitus, tremor. Caution should be taken in patients w/ a pacemaker or difibrillator (possible increase in sensing, pacing & fibrillation threshold).
Interactions
Effects enhnced by beta-blockers, antiarrhythmics or inhalation anesth. May intensify effects of other antihypertensives. Lithium (attenuated by verapamil, enhanced neurotoxicity). Increases plasma level of cyclosporing, theophylline, digoxin, carbamazepine. Effecs attenuated by rifampicin, phenytoin & phenobarbital. Effects of muscle relaxants may be potentiated. Rise in plasma levels by grapefruit juice & cimetidine. May increase plasma conc of certain beta-blockers(atenolol, metoprolol, propranolol), quinidine, prazosin, midazolam, aspirin (increased risk of bleeding), alcohol (reduced metabolism, increase in plasm levels). |
